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Plasma Lipids | Metabolism | Fundamentals of Biochemistry

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The cornerstone of this sqadia.com medical video lecture is the elaboration of plasma lipids. Initially, light is shed on lipids fractions in plasma and transport of plasma lipids. Then esterification and lipolysis are pursued. Subsequently, the focus is shifted towards adipose tissue hormones, the effect of drugs like methylxanthine, caffeine and theophylline on metabolism, and brown adipose tissue.

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Lecture Duration - 00:54:06
Release Date - April 2019

Watch complete lecture on sqadia.com -
sqadia.com/programs/plasma-lipids
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LIPIDS FRACTIONS IN PLASMA
Principal lipids functioning as plasma lipids are triacyl glycerol, natural fats, phospholipids, and steroids. Then transport of plasma lipids is comprehensively elaborated with the help of a diagram. After that, ultracentrifugation comes under consideration which illustrates that pure fat is less dense than water.

METABOLISM
Talking about the dynamic state of adipose tissue, Sidra Afzal informs that adipose tissues are not just static lump of fats rather they are in a dynamic state. Esterification and lipolysis are two mechanisms of metabolism. Esterification is the process of synthesis while in lipolysis breakdown takes place. Effect of glucose is presented lastly.

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ADIPOSE TISSUE HORMONES
Insulin inhibits the release of free FA from adipose tissue. Carrying on with discussion effect on enzymes in highlighted. After that detailed explanation of Prolactin is given. Catecholamines, glucagon, growth hormone, glucocorticoids, ACTH, and vasopressin are hormones that increase the rate of lipolysis.

EFFECT OF DRUGS ON METABOLISM
Effect of drugs Like methylxanthine, caffeine and theophylline inhibit hosphodiesterase enzyme. Subsequently, the fat mobilising substance is discussed. Moreover, assimilation of TGFA by adipose tissue along with characteristics of lipoprotein lipase are reported in this section.

BROWN ADIPOSE TISSUE
There are two types of storage fats i.e. white fat which is present in depot fats and the other is brown fat which is stored in some species including humans. Proceeding further, Sidra Afzal elucidates its role in thermogenesis. Moreover, radiographed illustrations are used to comprehensively explain the characteristics of brown adipose tissue. Alongside, the mechanism of heat production is also discussed.

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