G-Protein Coupled Receptors | Signalling Pathways | Physiology Animation | V-Learning
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When a ligand binds to the GPCR, conformational change occurs.
G-alpha dissociates from receptor and G beta-gamma, and GDP is replaced by GTP.
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Activated G-alpha can bind to adenylyl cyclase. It can also bind to phospholipase C. It can also activate a variety of other enzymes.
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