Asthma | Animation Video | Medical Pathology Education | V-Learning | sqadia.com
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This sqadia.com short video clip is the brief explanation of asthma.
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Asthma is a chronic disease characterized by recurrent attacks of breathlessness and wheezing, which vary in severity and frequency from person to person.
An allergen on entering into the airway is presented by the dendritic cells to the T-cells. The T-cells release IL-4 and IL-5. The later causes recruitment and activation of eosinophils. Whereas, the IL-4 triggers the activation of B-cells to synthesize IgE-antibodies.
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The binding of antigens with these antibodies causes degranulation. Thus, causing bronchial tube swelling and hence, the narrowing of the airways. This reduces the flow of air in and out of the lungs.
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