Infectious Mononucleosis | Animation Video | Medical Pathology | V-Learning | sqadia.com
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This sqadia.com short video clip is a brief explanation of Infectious mononucleosis.
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Infectious mononucleosis is cause by Epstein-Barr virus. In a susceptible sero-negative host, the virus in the contaminated saliva invades and replicates within epithelial cells of the salivary gland. It then enters B cells in the lymphoid tissues.
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Inside the lymph node, there are lymphoid follicles and antigens displayed on follicular dendritic cells. B cells migrate to edge of follicle where they contact effector CD4+ T cell. Activated B cells migrates back into the follicle and proliferate.
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