Buy L-(+)-Ergothioneine (EGT) powder (497-30-3) Manufacturers
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4 L-(+)-Ergothioneine Base Information
Name L-(+)-Ergothioneine (EGT)
CAS 497-30-3
Purity 98%
Chemical name (α-S)-α-Carboxy-2,3-dihydro-N,N,N-trimethyl-2-thioxo-1H-imidazole-4-ethanaminium inner salt
Synonyms Ergothionine;L-(+)-Ergothioneine;Erythrothioneine
Molecular Formula C9H15N3O2S
Molecular Weight 229.30
Melting Point 255-259° C
InChI Key SSISHJJTAXXQAX-ZETCQYMHSA-N
Form solid
Appearance white solid
Half Life around 30 days
Solubility Soluble in water (50 mg/ml), acetone, hot ethanol, and methanol.
Storage Condition -20°C (des.)
Application An antioxidant and free radical scavenger
Testing Document Available
05 L-(+)-Ergothioneine (EGT) General Description
L-Ergothioneine is a stable antioxidant that can be found under conditions of excessive oxidative stress in plant and animal tissue. L-ergothioneine has the ability to scavenge free radicals and protect cells from UV-induced ROS with higher efficiency than antioxidants coenzyme Q(10) or idebenone, thus making it more effective antioxidant. The compound has been shown to be a non-toxic thiol buffering antioxidant, enhance cell viability induced by hydrogen peroxide (H2O2), and inhibit DNA oxidation by peroxynitrite (ONOO-) in the human neuronal hybridoma cell line (N-18-RE-105).
L-(+)-Ergothioneine (EGT) powder (497-30-3)
06 L-(+)-Ergothioneine (EGT) (497-30-3) History
EGT is made in relatively few organisms, notably Actinobacteria, Cyanobacteria, and certain fungi. Ergothioneine was discovered in 1909 and named after the ergot fungus from which it was first purified, with its structure being determined in 1911.
07 L-(+)-Ergothioneine (EGT) Mechanism Of Action
l-(+) Ergothioneine is a naturally occurring thiol amino acid with antioxidant properties and potential benefits as a dietary supplement. Despite its century-old identification and wide distribution in human food, little is known of its mechanism of action and safety.
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