Antimycobacterial Drugs -II | Pharmacology Lectures | Medi

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Play, download and edit the free video Antimycobacterial Drugs -II | Pharmacology Lectures | Medical Online Education | V-Learning.

As Antimycobacterial drugs is a vast topic and it is necessary to explain every drug in detail, so Ms. Sidra Afzal made two lectures on this topic for the easy understanding of medical students. Previous lecture on Antimycobacterial Drugs – I classify the diseases caused by Mycobacteria and then explain the mechanism of action of drugs used for tuberculosis treatment.

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Lecture Duration - 00:40:34
Release Date - February 2020

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Drugs used for the treatment of the diseases caused by mycobacterium are collectively termed as Antimycobacterial Drugs. This mycobacterium lecture starts with the Classification of Antimycobacterial Agents.

Antimycobacterial Agents are classified as drugs used in Tuberculosis, Drug used in Leprosy and drug used for Atypical Mycobacteria. Then this antituberculosis video lecture explains the Ethionamide Pharmacokinetics. Ethionamide is chemically related to isoniazid and similarly blocks the synthesis of mycolic acids.

Furthermore, clinical uses of ethionamide and adverse effects are discussed. Resistance to ethionamide as a single agent develops rapidly in vitro and in vivo. There can be low-level cross-resistance between isoniazid and ethionamide.

Focus of this antituberculosis lecture is then shifted towards the Capreomycin. Capreomycin is a peptide Protein Synthesis Inhibitor antibiotic obtained from Streptomyces capreolus. Capreomycin mechanism of action, clinical uses along with adverse effects are discussed in detail.

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This antimycobacterial drugs lecture then explains the Cycloserine. It is a structural analog of d-alanine and it inhibits cell wall synthesis. Aminosalicylic acid is a folate synthesis antagonist that is active almost exclusively against M tuberculosis. Mechanism of action of Aminosalicylic acid and Fluoroquinolones is illustrated.

Dapsone is explained with the explanation of mechanism of action, Pharmacokinetics, clinical use, and adverse effects. Then this mycobacterium lecture focuses on the clofazimine. Complete mechanism of action with pharmacokinetics, clinical use and adverse effects are explained.

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